Medication overuse headache (MOH) is a common secondary headache disorder that occurs in individuals who frequently use pain medication to treat their headaches. MOH typically occurs in individuals who have a pre-existing headache disorder, such as migraines or tension-type headaches, and overuse medications like acetaminophen, ibuprofen, or triptans to manage their symptoms. The overuse of these medications can lead to a cycle of worsening headaches known as rebound headaches, where the medication itself triggers more frequent or severe headaches. MOH can be challenging to treat, as the withdrawal of the offending medication often leads to a temporary increase in headache frequency and severity. Treatment typically involves stopping the overused medication and transitioning to prevention strategies for managing headaches, such as lifestyle changes, stress management, and preventive medications. It is important for individuals with MOH to work closely with a healthcare provider to develop a treatment plan tailored to their specific needs and symptoms.